Prostate Cancer Home > Lupron Depot Drug Interactions

Medications used to treat diabetes, such as insulin, glitazones, metformin, and sulfonylureas, are the only drugs expected to interact with Lupron Depot. As a result, if you have diabetes and are taking Lupron Depot, your healthcare provider may adjust the doses of your diabetes medications and have you check your blood sugar more often.

An Overview of Interactions With Lupron Depot

Lupron Depot® (leuprolide acetate depot) is a prescription hormone medication that is given as an injection. Lupron Depot is not expected to interact with most medications. However, it may react with drugs used to treat diabetes, including:
  • Alpha-glucosidase inhibitors, such as:
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Last reviewed by: Kristi Monson, PharmD;
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