Prostate Cancer Home > Precautions and Warnings With Fentanyl Nasal Spray

Talk to your healthcare provider before using fentanyl nasal spray if you have any medical problems, such as low blood pressure, problems with alcohol or drug abuse, or a history of a seizure. Other precautions and warnings with fentanyl nasal spray involve the risk of becoming addicted to the medication, potential drug interactions, and the safety of using it when pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Using Fentanyl Nasal Spray?

Talk with your healthcare provider prior to using fentanyl nasal spray (Lazanda®) if you have:
  • Past or present drug or alcohol dependence or abuse problems
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Breathing problems, such as asthma, chronic obstructive pulmonary disease (COPD), or shortness of breath
  • A head injury, brain tumor, or increased pressure around the brain
  • A history of a seizure
  • A low heart rate or abnormal heart rhythm
  • Low blood pressure (hypotension)
  • Not already been taking a regularly scheduled opioid medication
  • Mental health conditions, such as depression or schizophrenia
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
Make sure to tell your healthcare provider about any medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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