Lupron Depot and Breastfeeding

In general, women who are breastfeeding should avoid Lupron Depot (leuprolide acetate depot). Based on how the drug is administered, it is unlikely to cause problems for a nursing infant; however, the effects Lupron Depot could have on breast milk production and on the infant are unknown, so it is best to discuss the issue with your healthcare provider.

Is It Safe to Take Lupron Depot While Breastfeeding?

Lupron Depot® (leuprolide acetate depot) is a prescription medication that decreases the production of sex hormones in the body. It is used to ease the symptoms of prostate cancer in men, to treat early puberty in children, and to manage endometriosis and uterine fibroids in women.
At this time, it is unknown if Lupron Depot passes through breast milk. Thus, it is not recommended for use in breastfeeding women.

More Information on Breastfeeding and Lupron Depot

Lupron Depot has not been studied in breastfeeding women. Therefore, it is unknown if the medicine passes through breast milk. It is also unknown if the medicine will harm a nursing child or affect breast milk production.
While this lack of information on Lupron Depot is certainly frustrating, it is important to understand that medicines are rarely studied in breastfeeding women, as this would usually expose an infant, who will not directly benefit from the medication, to possible risks.
Lupron Depot must be given as an injection to be active; it is not active when taken by mouth. Therefore, the drug would be unlikely to harm a nursing infant, who would ingest the medicine orally. However, because Lupron Depot affects estrogen levels in the body, it could potentially affect breast milk production.
In addition, all potential risks in nursing infants cannot be ruled out at this time. Therefore, Lupron Depot should not be used in nursing mothers.
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Lupron Depot Drug Information

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