Zytiga Drug Interactions

Combining Zytiga with codeine, tramadol, or various other drugs may cause negative interactions. Some of these reactions can increase the risk for side effects or decrease the effectiveness of the medications. Your healthcare provider may need to monitor you more closely, adjust your dosages, or recommend different medications if you are undergoing Zytiga treatment and are taking medications that may cause complications with this cancer drug.

Zytiga Medication Information

An Overview of Interactions With Zytiga

Zytiga™ (abiraterone acetate) may react with a number of other medications. Some of the drugs that can lead to interactions with Zytiga include but are not limited to:

Atomoxetine (Strattera^®)
Carvedilol (Coreg^®, Coreg CR^®)
Clopidogrel (Plavix^®)
Codeine
Colchicine (Colcrys^®)
CYP 3A4 inducer medications, such as:

Aminoglutethimide (Cytadren^®)
Bosentan (Tracleer^®)
Carbamazepine (Carbatrol^®, Epitol^®, Equetro^®, Tegretol^®)
Dexamethasone (Decadron^®, Dexpak^®, Maxidex^®)
Efavirenz (Sustiva^®)
Efavirenz, emtricitabine, and tenofovir (Atripla^®)
Etravirine (Intelence™)
Fosphenytoin (Cerebyx^®)
Nafcillin
Nevirapine (Viramune^®)
Oxcarbazepine (Trileptal^®)
Pentobarbital (Nembutal^®)
Phenobarbital (Luminal^®)
Phenytoin (Dilantin^®, Phenytek^®)
Primidone (Mysoline^®)
Rifabutin (Mycobutin^®)
Rifampin (Rifadin^®)
Rifapentine (Priftin^®)
St. John's wort

CYP 3A4 inhibitor medications, such as:

Amprenavir (Agenerase^®)
Atazanavir (Reyataz^®)
Clarithromycin (Biaxin^®)
Conivaptan (Vaprisol^®)
Darunavir (Prezista^®)
Delavirdine (Rescriptor^®)
Erythromycin
Fosamprenavir (Lexiva^®)
Imatinib (Gleevec^®)
Indinavir (Crixivan^®)
Isoniazid
Itraconazole (Sporanox^®)
Ketoconazole (Nizoral^®)
Lopinavir and ritonavir (Kaletra^®)
Miconazole
Nefazodone (Serzone^®)
Nelfinavir (Viracept^®)
Nicardipine (Cardene^®)
Posaconazole (Noxafil^®)
Quinidine
Ritonavir (Norvir^®)
Saquinavir (Fortovase^®, Invirase^®)
Telithromycin (Ketek^®)
Voriconazole (VFEND^®)

Dabigatran (Pradaxa^®)
Everolimus (Afinitor^®, Zortress^®)
Fesoterodine fumarate (Toviaz^®)
Iloperidone (Fanapt^®)
Nebivolol (Bystolic^®)
Silodosin (Rapaflo^®)
Tamoxifen (Nolvadex^®)
Tetrabenazine (Xenazine^®)
Thioridazine (Mellaril^®)
Topotecan (Hycamtin^®)
Tramadol (Rybix™ ODT, Ryzolt^®, Ultram^®, Ultram^® ER) or tramadol/acetaminophen (Ultracet^®).

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