Zytiga Drug Interactions

CYP 3A4 Inhibitor Medications
The liver breaks down Zytiga using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Combining Zytiga with one of these CYP 3A4 inhibitors may increase the level of Zytiga in your bloodstream, increasing your risk for side effects. Your healthcare provider may monitor you more closely for side effects if you take Zytiga with a CYP 3A4 inhibitor.
 
Dabigatran
Combining Zytiga with dabigatran can increase the levels of dabigatran in the bloodstream, which could increase the risk for side effects such as bleeding. Your healthcare provider may choose to give you a lower dabigatran dose if you take it with Zytiga.
 
Everolimus
Zytiga can increase the levels of everolimus in the body, possibly increasing your risk for everolimus side effects. Your healthcare provider may give you a lower everolimus dose if you take these medicines together.
 
Fesoterodine
Combining Zytiga with fesoterodine can increase the level of fesoterodine in your bloodstream. Your healthcare provider may monitor you more closely for fesoterodine side effects if you take this drug with Zytiga.
 
Iloperidone
Zytiga can increase the level of iloperidone in the body, which could increase your risk for side effects. Your healthcare provider may need to give you a lower iloperidone dose if you take it with Zytiga.
 
Nebivolol
Zytiga can increase blood levels of nebivolol. If you take these medicines together, your healthcare provider will likely monitor your blood pressure and heart rate, and adjust your nebivolol dose if needed.
 
Silodosin
Taking Zytiga with silodosin may increase blood levels of silodosin, possibly increasing the risk for side effects. In general, it is not recommended to take silodosin with Zytiga.
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Zytiga Medication Information

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