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Zoladex Warnings and Precautions
Zoladex may cause bone loss or allergic reactions, so make sure to discuss the safety precautions and warnings with your healthcare provider before starting treatment. This implant is not suitable for everyone, and may cause problems like high blood sugar levels, drug interactions, and mood changes. Contact your healthcare provider if your symptoms do not go away after a few weeks of treatment.
What Should I Tell My Healthcare Provider?
Talk with your healthcare provider prior to using Zoladex® (goserelin acetate implant) if you have:- An inability to urinate (urinary tract obstruction)
- Cancer that has spread to the spine or urinary tract
- Unexplained vaginal bleeding
- Heart disease
- High blood pressure (hypertension)
- High cholesterol
- Diabetes
- A history of heart attack or stroke
- Tumors of the pituitary gland
- Osteoporosis or risk factors for osteoporosis, such as:
- A family history of the condition
- Smoking
- Alcohol use
- A mental health condition, such as depression, anxiety, or schizophrenia
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Zoladex and Pregnancy)
- Breastfeeding (see Zoladex and Breastfeeding).
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD