Zoladex and Pregnancy

More Information on Zoladex and Pregnancy

Zoladex has not been adequately studied in pregnant women. However, it caused pregnancy loss when given to rats and rabbits. It also caused umbilical hernia (when part of the intestines bulges through an opening in the abdominal muscle around the belly button) in the rat and rabbit offspring, especially at higher doses.
This medication also decreases the production of estrogen by the ovaries. Estrogen helps support uterine growth and maintains the lining of the uterus during pregnancy. By depleting estrogen levels, Zoladex may lead to miscarriage. However, there are cases of women becoming pregnant, and maintaining the pregnancy, while using Zoladex.
In most cases, Zoladex should not be used in pregnant women. It may be used in pregnant women to manage the symptoms of advanced breast cancer, if the healthcare provider believes the benefits of easing the symptoms of the advanced cancer outweigh the risks of miscarriage and fetal harm.
Pregnancy should be ruled out before a woman starts taking this medicine. All women who may become pregnant should use a nonhormonal method of birth control while using Zoladex, and for at least 12 weeks after treatment ends. Examples of nonhormonal birth control include:
  • Condoms
  • Some intrauterine devices (IUDs)
  • The sponge.
Women who receive Zoladex normally stop having monthly periods. However, this drug should not be used as a form of birth control. It is still possible to become pregnant while using this medication.

Final Thoughts

Zoladex should not be used in pregnant women or women who may become pregnant, except for women with advanced breast cancer. If you are pregnant or thinking of becoming pregnant, let your healthcare provider know. He or she will consider both the benefits and risks of Zoladex use during pregnancy before making a recommendation in your particular situation.
Pregnancy and Pain

Zoladex Drug Information

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