Supprelin LA Uses

How Does This Medicine Work?

Supprelin LA is a synthetic (manufactured) form of gonadotropin-releasing hormone (GnRH), a naturally occurring hormone in the body. It controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland (a tiny gland located beneath the brain). LH and FSH stimulate the production of testosterone in the testes and estrogen in the ovaries.
Supprelin LA works by overstimulating the pituitary gland. When overstimulated, the pituitary does not make as much LH and FSH. As a result, the testes stop making testosterone and the ovaries stop making estrogen. This causes testosterone (in boys) and estrogen (in girls) levels to decrease, temporarily stopping puberty.
The Supprelin LA implant is specially formulated to slowly release medicine into the body over a 12-month period. This allows for once-a-year dosing.

Can Children Use Supprelin LA?

This medication is approved for use in children as young as two years old. This medication has not been adequately studied in children younger than two years of age.

Is It Safe for Older Adults?

Supprelin LA is not approved for older adults, as it has not been adequately studied in this age group. A similar medication, Vantas®, is approved for use in older men with certain types of prostate cancer.

Off-Label Uses for Supprelin LA

On occasion, healthcare providers may recommend medicines for something other than their approved uses. This is known as an "off-label" use. At this time, there are no commonly accepted off-label uses for Supprelin LA.
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Supprelin LA Drug Information

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