Supprelin LA Dosage

Regardless of your age or weight, there is only one dosage of Supprelin LA: one implant inserted just below the skin of the upper arm. This implant is designed to slowly release the medicine over a 12-month period, after which a new implant may be inserted if treatment is to be continued.

An Introduction to Dosing With Supprelin LA

There is only one standard dose of Supprelin® LA (histrelin implant), regardless of your age or weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Supprelin LA Dosage for Central Precocious Puberty

The usual Supprelin LA dose for treating central precocious puberty is one implant every 12 months. Each implant contains Supprelin LA 50 mg and provides a continuous release of 65 mcg per day for one year (plus a few additional weeks to allow for flexible scheduling of the next dose).
The implant is inserted by a healthcare provider as part of a minor surgical procedure. After numbing the arm, the healthcare provider will make a small incision (a cut). The implant will be inserted under the skin through this incision. The incision will then be closed with stitches, special surgical tape, or both.
The Supprelin LA implant must be removed after one year, at which time a new implant can be inserted. The implant can also be removed at any time, if treatment needs to be stopped. It is generally recommended that treatment with Supprelin LA end before age 11 in girls and age 12 in boys, to allow for normal puberty to occur.

General Information on Using Supprelin LA

Some considerations to keep in mind during treatment with Supprelin LA include the following:
  • Supprelin LA comes as an implant that is inserted subcutaneously (just below the skin) in the inner part of the upper arm once a year.
  • The implant is inserted by a healthcare provider in a healthcare setting, such as a doctor's office or clinic.
  • You should keep your child's arm clean and dry for 24 hours after the implant is inserted. Also, your child should avoid exercise and activities that could cause the incision site to get bumped. This will help the incision heal, and decrease the likelihood of the implant coming out.
  • Your child's healthcare provider must remove the implant after approximately one year. If your child will continue treatment, a new implant may be inserted in the same area, or moved to a different site on the upper arm.
  • The Supprelin LA implant will provide a few additional weeks of medicine, so that your child's appointments do not need to be exactly one year apart.
  • For this drug to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your child's dosage of Supprelin LA, please talk to your healthcare provider or pharmacist.
6 Quick Tips for Getting Kids to Take Medicine

Supprelin LA Drug Information

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