PROVENGE® (sipuleucel-T) is a medicine prescribed to treat prostate cancer that has spread to other areas of the body (metastasized). Specifically, it is used in men who have not responded to hormone therapy and have minimal or no prostate cancer symptoms.
As a prostate cancer therapy, PROVENGE works by using a person's own immune cells. The cells are mixed with an active protein designed to help stimulate an immune response to prostate cancer.
Clinical studies have shown that PROVENGE therapy can help increase survival time when given to men with metastatic, hormone refractory prostate cancer (prostate cancer that has spread beyond the prostate, and is no longer responsive to hormone therapy). In these studies, men given PROVENGE survived an average of four months longer than men given a placebo (an injection that did not contain the active ingredient).
(For a closer look at this prostate cancer therapy, click PROVENGE. This Web segment describes how this medicine is given, potential side effects that may occur, and why this medicine may not be a safe choice for some people.)