Pomegranates may provide several health benefits, such as lowering cholesterol and blood pressure. Most people eat the seeds or drink the juice of the pomegranate, although extracts and supplements are also available. Although it seems unlikely that pomegranates would cause side effects, they may cause allergic reactions or swelling of the mouth or throat. Before using pomegranates medicinally, talk to your healthcare provider about possible drug interactions or other potential complications that could occur.