By stopping production of testosterone in the testes and estrogen in the ovaries, Zoladex® (goserelin acetate implant) can help treat advanced prostate cancer, advanced breast cancer, and various gynecological conditions. It is approved for use in adults age 18 and older.
Although this hormone medication may be an effective drug for many people, not everyone can use this product. Information on Zoladex should be discussed with your healthcare provider before starting treatment to minimize risks and to help ensure safe treatment. For example, you may not be able to use this medicine if you have certain allergies, if you are taking certain medications, or if you are pregnant or breastfeeding.
Although most people tolerate this medication well, side effects are possible and can include mood changes, hot flushes, and headaches. In most cases, however, reactions to the drug tend to be mild and easy to treat.
(Click Zoladex for more information on this product, including a detailed description of the medicine's effects, a list of potential side effects that may occur with treatment, and dosing tips.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 21, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 21, 2011.
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