If you have prostate cancer, breast cancer, or endometriosis, a healthcare provider may prescribe Zoladex® (goserelin acetate implant). Given by injection, this implant is inserted just under the skin on the abdomen (stomach). The implant does not have to be removed from the body, as it dissolves gradually over either a 4-week or 12 -week period (depending on which strength of the medicine is used).
Zoladex works by overstimulating the pituitary gland, which causes the body to stop producing testosterone in men and estrogen in women. This decrease in testosterone and estrogen is responsible for the drug's beneficial effects.
(Click Zoladex for more information on how this implant is injected, possible side effects to be aware of, and general safety concerns to review before beginning treatment.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 21, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 21, 2011.
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