Prostate Cancer Home > Zoladex Drug Interactions

If you have diabetes and use medications to control your glucose levels, you may not be able to use Zoladex. Drug interactions can occur when Zoladex is used with certain diabetes medications, such as metformin, insulin, or glitazones. If you are using Zoladex with such a medicine, you may need to check your blood sugar levels more frequently.

An Overview of Interactions With Zoladex

Zoladex® (goserelin acetate implant) is a prescription medication used in the treatment of certain gynecological conditions, as well as prostate and breast cancers. It belongs to a class of drugs called gonadotropin-releasing hormone (GnRH) agonists.
 
Zoladex may cause negative interactions when combined with certain drugs used to treat diabetes. Some of these diabetes medications may include:
 
  • Alpha-glucosidase inhibitors, such as:
 
 
  • Bromocriptine (Cycloset™)
  • Dipeptidyl peptidase-4 (DPP-4) inhibitors and combination DPP-4 medications, such as:
 
 
  • Glitazones and glitazone combination medications, such as:
 
 
  • Glucagon-like peptide 1 receptor agonists, such as:
 
 
  • Insulin of any type
  • Meglitinides, such as:
 
 
 
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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