Prostate Cancer Home > Zoladex Drug Interactions
If you have diabetes and use medications to control your glucose levels, you may not be able to use Zoladex. Drug interactions can occur when Zoladex is used with certain diabetes medications, such as metformin, insulin, or glitazones. If you are using Zoladex with such a medicine, you may need to check your blood sugar levels more frequently.
An Overview of Interactions With Zoladex
Zoladex® (goserelin acetate implant) is a prescription medication used in the treatment of certain gynecological conditions, as well as prostate and breast cancers. It belongs to a class of drugs called gonadotropin-releasing hormone (GnRH) agonists.Zoladex may cause negative interactions when combined with certain drugs used to treat diabetes. Some of these diabetes medications may include:
- Alpha-glucosidase inhibitors, such as:
- Bromocriptine (Cycloset™)
- Dipeptidyl peptidase-4 (DPP-4) inhibitors and combination DPP-4 medications, such as:
- Alogliptin (Nesina®), alogliptin and metformin (Kazano®), and alogliptin and pioglitazone (Oseni®)
- Linagliptin (Tradjenta™)
- Linagliptin and metformin (Jentadueto™)
- Saxagliptin (Onglyza™)
- Saxagliptin/metformin ER (Kombiglyze™ XR)
- Sitagliptin (Januvia®)
- Sitagliptin and metformin (Janumet®)
- Sitagliptin and metformin XR (Janumet® XR)
- Glitazones and glitazone combination medications, such as:
- Pioglitazone hydrochloride (Actos®)
- Pioglitazone and glimepiride (Duetact®)
- Pioglitazone and metformin (Actoplus Met®)
- Pioglitazone and metformin XR (Actoplus Met® XR)
- Rosiglitazone (Avandia®)
- Rosiglitazone and glimepiride (Avandaryl®)
- Rosiglitazone and metformin (Avandamet®)
- Glucagon-like peptide 1 receptor agonists, such as:
- Exenatide (Byetta®)
- Liraglutide (Victoza®)
- Insulin of any type
- Meglitinides, such as:
- Nateglinide (Starlix®)
- Repaglinide (Prandin®)
- Metformin (Glucophage®, Glucophage XR®, Fortamet®, Glumetza®, Riomet®)
- Sulfonylureas or sulfonylurea combination medications, such as:
- Chlorpropamide (Diabinese®)
- Glimepiride (Amaryl®)
- Glimepiride and pioglitazone (Duetact®)
- Glimepiride and rosiglitazone (Avandaryl®)
- Glipizide (Glucotrol®, Glucotrol XL®)
- Glipizide and metformin (Metaglip®)
- Glyburide (DiaBeta®, Micronase®, Glynase®)
- Glyburide and metformin (Glucovance®)
- Tolazamide (Tolinase®)
- Tolbutamide (Orinase®).