Prostate Cancer Home > Zoladex Dosage

The specific amount of Zoladex you receive will depend on whether this medicated implant will be used to treat prostate cancer, breast cancer, or endometriosis. This implant is designed to slowly release the medicine over either a 4-week or 12-week period. It is inserted just beneath the skin on the stomach, and releases the medicine as it dissolves in the body.

An Introduction to Dosing With Zoladex

The dose of Zoladex® (goserelin acetate implant) your healthcare provider recommends will vary, depending mostly on the reason you are using the medication. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Zoladex Dosage for Prostate Cancer

The standard dose of Zoladex for prostate cancer is 3.6 mg every 4 weeks (28 days) or 10.8 mg every 12 weeks. The usual amount when used in combination with flutamide for the treatment of Stage II2-III (Stage B2-C) prostate cancer (cancer that has not spread or metastasized) is 3.6 mg followed by 10.8 mg four weeks (28 days) later. The 3.6-mg dose should be given eight weeks before the start of radiation treatment.

Zoladex Dose for Breast Cancer

The standard dosage of Zoladex for managing the symptoms of advanced breast cancer is 3.6 mg every 4 weeks (28 days). This drug may be used long-term in the treatment of advanced breast cancer.

Zoladex Dosage for Endometriosis

The standard dose of Zoladex for the treatment of endometriosis is 3.6 mg every four weeks (28 days) for six months. If symptoms recur after the initial six-month treatment course, your healthcare provider may need to check your bone health before treating you with Zoladex again.
In some cases, this medicine may be given with estrogen and/or progestin therapy. This is because estrogen and progestin may help reduce some Zoladex side effects, such as bone thinning, hot flushes, and vaginal dryness.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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