Prostate Cancer Home > Zoladex and Breastfeeding

Women should not use Zoladex (goserelin acetate implant) while breastfeeding. Because this drug affects estrogen production, it could, in theory, affect breast milk and potentially harm a nursing infant. Before using this medicine while breastfeeding, discuss the potential risks with your healthcare provider.

Can Breastfeeding Women Use Zoladex?

Zoladex® (goserelin acetate implant) is a prescription medication used to ease the symptoms of advanced breast cancer, prostate cancer, and endometriosis. It is also used in women with abnormal uterine bleeding to thin the lining of the uterus before endometrial ablation (a procedure used to destroy the lining of the uterus, known medically as the endometrium).
 
At this time, little information is available on Zoladex and breastfeeding. Based on the actions of the medicine and the lack of currently available information, Zoladex is not recommended for use in women who are nursing.
 

More Information on Zoladex and Breastfeeding

In animal studies, Zoladex has been shown to pass through the breast milk of rats. However, there have been no studies using Zoladex in breastfeeding women. Therefore, it is unknown whether the medicine will pass through human breast milk. It is also unknown if the drug will harm a nursing child or affect breast milk supply or quality.
 
Zoladex works by decreasing the production of estrogen (in females) and testosterone (in males) in the body. Because of its effects on hormone levels, Zoladex could affect breast milk and potentially harm a nursing infant. Therefore, this drug should not be used in nursing mothers.
 

Talking With Your Healthcare Provider

You should discuss breastfeeding and Zoladex use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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