Prostate Cancer Home > Trelstar Side Effects

In clinical studies, up to 73 percent of people receiving Trelstar reported hot flashes; this was the most commonly reported side effect. Other common reactions included high blood pressure, urinary tract infection, and muscle pain. If you are undergoing treatment with Trelstar and notice any problems, or if something "just doesn't seem right," notify your healthcare provider right away.

An Introduction to Trelstar Side Effects

Just like any medicine, Trelstar® (triptorelin pamoate) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Trelstar. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Trelstar

Trelstar has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people receiving the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, common adverse reactions to Trelstar included:
Other common reactions, occurring in 1.1 to 4.6 percent of people, included:
  • Painful urination
  • Pain at the injection site
  • Nausea and vomiting
  • Dizziness
  • Fatigue
  • Breast tenderness, pain, or enlargement
  • Decreased libido (low sex drive)
  • Insomnia
  • Frequent mood changes
  • Decrease in red blood cells (anemia)
  • Itching
  • Chest pain
  • Decreased appetite
  • Coughing
  • Rash
  • Heartburn or indigestion
  • Leg cramps
  • Constipation or diarrhea
  • Stomach pain
  • Sore throat
  • Shortness of breath
  • Weakness or lack or energy
  • Eye pain
  • Inflammation or swelling of the lining of the eye (conjunctivitis).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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