A healthcare provider may prescribe PROVENGE® (sipuleucel-T) to treat certain cases of prostate cancer. But what is PROVENGE and how does it work?
This prescription hormone medicine is approved to treat metastatic prostate cancer (cancer that has spread to other areas in the body) that is not adequately responding to hormone therapy. It is only approved for use in adult men who are not experiencing any cancer symptoms or who have only minimal symptoms.
The medicine is unique in that it uses a person's own immune cells to treat prostate cancer. These immune cells are mixed with a certain protein that activates them to attack prostate cancer cells.
(Click PROVENGE for a more complete overview of what PROVENGE is prescribed for and how it works. This article also discusses potential side effects, dosing guidelines, and some general safety precautions to be aware of before beginning treatment.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
PROVENGE Web site. Available at: http://www.provenge.com. Accessed July 13, 2011.
Food and Drug Administration Web site. Vaccines, Blood and Biologics, Approved Products. PROVENGE. Available at: http://www.fda.gov/BiologicsBloodVaccines/CellularGeneTherapyProducts/ApprovedProducts/ucm210012.htm. Accessed July 13, 2011.
Food and Drug Administration Web site. Vaccines, Blood and Biologics, Resources for Healthcare Providers. Available at: http://www.fda.gov/BiologicsBloodVaccines/ResourcesforYou/HealthcareProviders/default.htm. Access July 13, 2011.
Food and Drug Administration Web site. Vaccines, Blood and Biologics, Questions and Answers about PROVENGE. Available at: http://www.fda.gov/BiologicsBloodVaccines/CellularGeneTherapyProducts/ApprovedProducts/ucm210037.htm. Accessed July 13, 2011.
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