Prostate Cancer Home > Nilandron Side Effects
Problems seeing in the dark, hot flushes, and general body pain are some of most commonly reported side effects of Nilandron. While reactions such as these are generally mild, there are some potentially dangerous side effects that require medical treatment. Contact your healthcare provider right away if you develop chest pain, blood in your urine, or other potentially serious problems.
An Introduction to Nilandron Side EffectsJust like any medicine, Nilandron® (nilutamide) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Nilandron. Your healthcare provider can discuss a more complete list with you.)
Common Side Effects of NilandronNilandron has been studied extensively in clinical studies. In these studies, one group of people received the real medication, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what Nilandron side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common side effects of Nilandron included:
- Hot flushes -- in up to 66.5 percent of men
- Problems seeing in the dark -- up to 56.9 percent
- General body pain -- up to 26.8 percent
- Nausea -- up to 23.9 percent
- Constipation -- up to 19.6 percent
- Weakness or fatigue -- up to 19.1 percent
- Testicular atrophy (shrinking of the testicles) -- up to 16.3 percent
- Insomnia -- up to 16.3 percent
- Headaches -- up to 13.9 percent
- Increase in liver enzymes -- up to 12.9 percent
- Swelling in the arms, hands, legs, ankles, or feet -- up to 12.4 percent
- Back pain -- up to 11.5 percent
- Decreased libido (sex drive) -- up to 11.0 percent
- Impotence (erectile dysfunction, or ED) -- up to 11.0 percent
- Decreased appetite -- up to 11.0 percent.
Other common side effects, occurring in 5.3 to 10.5 percent of men, included:
- Breast enlargement
- Shortness of breath
- Abdominal (stomach) pain
- Increased blood pressure (hypertension)
- Urinary tract infections (UTIs)
- Blood in the urine
- Vision problems, including abnormal color vision and difficulty adapting to light
- Upper respiratory tract infections
- Chest pain
- Flu-like symptoms
- Decrease in red blood cells (anemia)
- Needing to get up in the middle of the night to urinate
- Bone pain
- Indigestion or heartburn
- Dry skin
- Loss of body hair
- Decreased sensation of touch.