Eligard is a medication used in the treatment of prostate cancer. Available as an injection, it works by causing the pituitary gland to produce less testosterone. With less testosterone available, prostate cancer cells are not able to grow as readily and symptoms diminish. The drug is injected just beneath the skin every one, three, four, or six months, depending on what your healthcare provider recommends.
What Is Eligard?
Eligard® (leuprolide acetate) is a prescription medication approved to ease the symptoms of advanced prostate cancer. It is not a prostate cancer cure. Eligard is given by an injection just beneath the skin (subcutaneously) every one, three, four, or six months. It contains leuprolide, a synthetic form of the naturally occurring gonadotropin-releasing hormone (GnRH).
Eligard contains the same active ingredient as Lupron® (leuprolide acetate) and Lupron Depot® (leuprolide acetate depot). All three medicines are approved for use in advanced prostate cancer, and are given as an injection. However, while Eligard and Lupron are given as a subcutaneous injection, Lupron Depot is given as an injection into the muscle (an intramuscular injection).
One of the main differences between these medicines is how often they are given. Lupron is given once a day; Eligard every one, three, four, or six months; and Lupron Depot every one month, three months, or four months.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Eligard [package insert]. Bridgewater, NJ: sanofi-aventis U.S. LLC;2011 March.
Eligard Web site. Available at: http://www.eligard.com. Accessed June 14, 2011.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob. Accessed June 14, 2011.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed June 14, 2011.
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