Lupron Depot

Lupron Depot can be used to manage conditions ranging from uterine fibroids to prostate cancer to precocious puberty. It comes in the form of a powder that is mixed into a liquid and injected into a muscle. The medication works by slowing down or blocking the release of sex hormones. This causes certain effects in the body, depending on the condition being treated.

What Is Lupron Depot?

Lupron Depot® (leuprolide acetate depot) is a long-acting prescription medication that contains a synthetic form of gonadotropin-releasing hormone (GnRH). GnRH is a naturally occurring hormone that helps control the production of sex hormones in the body.
 
Lupron Depot is available in a variety of strengths and forms, including one-month, three-month, four-month, and pediatric forms. The different Lupron Depot products are approved to:
 
  • Reduce symptoms of advanced prostate cancer
  • Manage symptoms of endometriosis (a condition in which the tissue that normally lines the uterus grows outside the uterus)
  • Improve anemia before surgery for uterine fibroids (when used in combination with iron)
  • Treat precocious (early) puberty in children.
     
Lupron Depot contains the same active ingredient as Lupron® (leuprolide acetate). However, Lupron is given once a day as a subcutaneous injection, into the layer of tissue just beneath the skin. Lupron Depot is given every one to four months as an injection into the muscle (intramuscular or IM injection).
 
(Click Lupron Depot Uses for more information on this topic, including possible off-label uses.)
 

Who Makes This Medication?

Lupron Depot is manufactured by Takeda Pharmaceutical Company Limited for Abbott Laboratories.
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
 
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