Lupron Depot Treatment for Breast Cancer

The hormone medication Lupron Depot® (leuprolide acetate depot) is approved to treat the following conditions:
  • Advanced prostate cancer
  • Endometriosis (a condition in which endometrial tissue grows in other areas of the body)
  • Uterine fibroids (noncancerous tumors in the uterus)
  • Central precocious puberty (puberty that occurs too soon) in children.
Lupron Depot is similar to gonadotropin-releasing hormone (GnRH), a hormone found naturally in the body. GnRH controls the release of two other hormones from the pituitary gland: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These two hormones stimulate the production of sex hormones (testosterone and estrogen) in the ovaries and testicles.
Sometimes drugs are used to treat a condition they are not officially approved to treat. This is called an "off-label" use. Prescribing Lupron Depot as a treatment for breast cancer is an off-label use.
(Click Lupron Depot Uses to learn more about the conditions this drug can treat, how it works for these purposes, and additional off-label uses.)
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