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Jevtana Side Effects
Anemia, nausea, and low levels of certain white blood cells are some of the most common side effects of Jevtana. As with any chemotherapy medication, some of the most common side effects can be quite dangerous and most people will experience significant reactions. Tell your healthcare provider right away if you experience chest pain, difficulty breathing, or severe vomiting when receiving this drug.
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Just like any medicine, Jevtana® (cabazitaxel) can cause side effects. With a majority of medications, the most common side effects typically are bothersome but not usually dangerous. However, as is typical with chemotherapy medications, some of the most common side effects of Jevtana can be quite dangerous. Most people will experience significant side effects with this medication.
(This article covers many, but not all, of the possible side effects with Jevtana. Your healthcare provider can discuss a more complete list with you.)
Jevtana has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people given Jevtana plus prednisone were documented and then compared to those that occurred in a group of people who received a different chemotherapy drug (mitoxantrone) plus prednisone.
Based on these studies, the most common bothersome (but not usually dangerous) Jevtana side effects included:
- Anemia -- in up to 98 percent of people (see Chemotherapy and Anemia)
- Leukopenia (low levels of a certain type of white blood cell called leukocytes) -- up to 96 percent
- Neutropenia (low levels of another type of white blood cell called neutrophils) -- up to 94 percent
- Thrombocytopenia (low levels of blood platelets) -- up to 48 percent (see Blood Clotting Problems and Chemotherapy)
- Diarrhea -- up to 47 percent (see Chemotherapy-Induced Diarrhea)
- Fatigue -- up to 37 percent
- Nausea -- up to 34 percent (see Chemotherapy and Nausea).
Other common reactions, occurring in 5 to 22 percent of people, included:
- An irregular heart rhythm (arrhythmia)
- Vomiting
- Constipation
- Abdominal pain (stomach pain)
- Indigestion or heartburn
- General weakness
- Fever
- Swelling in the hands, legs, ankles, or feet
- Inflammation of the mouth or other mucous membranes (see Mouth and Gum Problems During Chemotherapy)
- Pain
- A urinary tract infection (UTI), such as a bladder infection
- Weight loss
- Loss of appetite
- Dehydration
- Back pain
- Joint pain
- Muscle spasms
- Nerve problems in the hands or feet, which may cause pain or unusual sensations (see Nerve and Muscle Problems During Chemotherapy)
- Change of taste
- Dizziness
- Headaches
- Blood in the urine
- Painful urination
- Shortness of breath
- Coughing
- Hair loss (see Chemotherapy and Hair Loss)
- Low blood pressure (hypotension).
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD