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Firmagon Drug Interactions
To help ensure your safety, let your healthcare provider know about any other medications, vitamins, or supplements you are taking before beginning treatment with Firmagon. For example, combining Firmagon with certain drugs that cause changes in heart rhythm can lead to interactions. Because these heart rhythm problems may lead to life-threatening complications, do not combine Firmagon with Cipro, Coartem, or certain other medicines.
An Overview of Interactions With Firmagon
Firmagon® (degarelix) is a prescription hormone therapy approved to treat advanced prostate cancer. This medication may react with medications that cause a certain change in the heart rhythm, known as QT prolongation. Some of the drugs that may cause interactions with Firmagon include but are not limited to:- Artemether/lumefantrine (Coartem®)
- Ciprofloxacin (Cipro®, Cipro® XR)
- Dronedarone (Multaq®)
- Nilotinib (Tasigna®)
- Pimozide (Orap®)
- Quinine (Qualaquin®)
- Thioridazine (Mellaril®)
- Ziprasidone (Geodon®).
(Click QT-Prolonging Medications for a more complete list of medications that may interact with Firmagon.)
Firmagon Drug Interactions Explained
Firmagon can potentially cause a certain change in the heart rhythm known as QT prolongation. In general, this medication should not be combined with any other medication that can also cause QT prolongation, due to the risk of a life-threatening arrhythmia.
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD