Fentanyl Nasal Spray Dosage

Before recommending a dosage of fentanyl nasal spray, your healthcare provider will consider other medications you are taking and your level of pain, among other things. The typical starting amount for this nasal spray is usually 100 mcg, which is given as one spray into one nostril. It is used on an as-needed basis every two hours, but not to exceed four doses a day.

An Introduction to Your Dosage of Fentanyl Nasal Spray

The dose of fentanyl nasal spray (Lazanda®) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your level of pain
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

Fentanyl Nasal Spray Dosing Guidelines

The standard initial dosage of fentanyl nasal spray for breakthrough pain is 100 mcg (given as one spray into one nostril) no more often than every two hours, for a maximum of four doses a day. If this dosage provides adequate pain relief within 30 minutes, it will be used for future episodes of breakthrough pain.
 
If the initial 100-mcg dosage does not provide adequate pain relief within 30 minutes, the amount will be slowly increased until an adequate amount is found or side effects become intolerable. Doses above 800 mcg have not been studied in clinical trials.
 
Your healthcare provider may need to periodically adjust your fentanyl nasal spray dose if your underlying pain level changes, your long-acting opioid dose changes, or you develop side effects. It is important that you work closely with your healthcare provider throughout treatment to make sure you remain on the most appropriate dosage for your individual situation.
 
Fentanyl nasal spray must be given in addition to a regularly scheduled opioid narcotic for underlying, persistent pain. If you stop taking an opioid pain medication on a regular basis, you will also need to stop using fentanyl nasal spray.
 
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Fentanyl Nasal Spray Information

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