The following sections explain in detail the potentially negative interactions that can occur when docetaxel is combined with any of the drugs listed above.

Certain Antibiotics or Antifungals

Combining certain antibiotics or antifungals and docetaxel may increase the level of docetaxel in your blood, increasing your risk of docetaxel side effects. Talk to your healthcare provider before taking these medications together.

Certain Anticonvulsants

Combining docetaxel with certain anticonvulsants (seizure medications) can decrease the level of docetaxel in your blood, perhaps making it less effective. Talk to your healthcare provider before taking these medications together.

Cyclosporine (Gengraf, Neoral, Sandimmune)

Combining cyclosporine with docetaxel may increase the level of docetaxel in your blood, increasing your risk of docetaxel side effects. Talk to your healthcare provider before taking these medications together.

Live Vaccinations

Because chemotherapy medications (including docetaxel) can suppress the immune system, it is generally best to avoid live vaccinations while receiving chemotherapy treatment.

Rifamycin Antibiotics

Combining docetaxel with rifamycin antibiotics can affect the level of docetaxel in your blood. Talk to your healthcare provider before taking these medications together.

Final Thoughts on Drug Interactions With Docetaxel

It is possible that not all docetaxel drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with docetaxel that may apply to you.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

Docetaxel

Docetaxel Side Effects

What Is Docetaxel Used For?

Docetaxel Dosing

Drug Interactions With Docetaxel

Precautions and Warnings With Docetaxel

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