Prostate cancer cells grow in response to androgens (male sex hormones). Casodex is a nonsteroidal androgen receptor inhibitor, sometimes called an antiandrogen. It works by binding to androgen receptors in the prostate and blocking the effect of naturally occurring androgens. This helps prevent the growth of prostate cancer cells.
Casodex is used in combination with a gonadotropin-releasing hormone (GnRH) agonist medicine. GnRH agonists reduce the amount of testosterone made by the body. Thus, Casodex blocks the action of the remaining testosterone.
Casodex is not approved for use in people younger than 18 years of age, as it has not been adequately studied in this age group. Low-dose Casodex has been studied in boys with a condition in which puberty occurs earlier than normal (known medically as precocious puberty). Although there were no serious side effects in the study, more studies are needed to determine if the medication is effective for this use.
Casodex is commonly used in older adult males with prostate cancer. No dosage adjustments are needed based on age.
Off-Label UsesOn occasion, your healthcare provider may recommend this product for something other than the condition discussed in this article. This is known as an "off-label" use. Using Casodex in earlier stages of prostate cancer would be considered an off-label use.